10. Hub bias and statistical comparison

10. Hub bias and statistical comparison

figure
Figure 14. Hub-bias panels: NetPert top-20 mean out-degree 1097, betweenness 1286–1196, overall 527.
MethodTop-20 mean out-degree
NetPert1096.6
Betweenness (driver-to-response)1286.2
Betweenness (full network)1195.8
Out-degree2703.1
Driver personalised PageRank2069.8
Overall (1,200 genes)526.8

Head-to-head top-20 hubbiness on the network (no ground truth; agreement measures only).

Hub supplement ()

Top-20 betweenness-subset genes (subnetwork)
Top-20 betweenness-subset genes (subnetwork)
Driver-to-response betweenness on the same subnetwork.
Top-20 betweenness genes (full 17k network)
Top-20 betweenness genes (full 17k network)
Betweenness on the full IID+TRRUST network.
Top-20 hubs by out-degree (full network)
Top-20 hubs by out-degree (full network)
Raw connectivity leaders for hub-bias context.
NetPert losers
NetPert losers
Shortest-path hubs that diffusion down-weights.
NetPert vs out-degree
NetPert vs out-degree
Spearman rho=0.51 over 1200 genes.